Publications Paediatric Pneumology

2016

Goutaki M, Meier AB, Halbeisen FS, Lucas JS, Dell SD, Maurer E, Casaulta C, Jurca M, Spycher BD, Kuehni CE. Clinical manifestations in primary ciliary dyskinesia: systematic review and meta-analysis. Eur Respir J. 2016 Oct;48(4):1081-1095 PMID: 27492829

Kobbernagel HE, Buchvald FF, Haarman EG, Casaulta C, Collins SA, Hogg C, Kuehni CE, Lucas JS, Omran H, Quittner AL, Werner C, Nielsen KG. Study protocol, rationale and recruitment in a European multi-centre randomized controlled trial to determine the efficacy and safety of azithromycin maintenance therapy for 6 months in primary ciliary dyskinesia. BMC Pulm Med. 2016 Jul 22;16(1):104. PMID: 27450411

Trippel M, Casaulta C, Sokollik C. Heterotopic gastric mucosa: Esophageal inlet patch in a child with chronic bronchitis. Dig Endosc. 2016 Sep;28(6):688. PMID: 27307349

Schögler A, Stokes AB, Casaulta C, Regamey N, Edwards MR, Johnston SL, Jung A, Moeller A, Geiser T, Alves MP. Interferon response of the cystic fibrosis bronchial epithelium to major and minor group rhinovirus infection. J Cyst Fibros. 2016 May;15(3):332-9. PMID: 26613982

Alves MP, Schögler A, Ebener S, Vielle NJ, Casaulta C, Jung A, Moeller A, Geiser T, Regamey N. Comparison of innate immune responses towards rhinovirus infection of primary nasal and bronchial epithelial cells. Respirology. 2016 Feb;21(2):304-12. PMID: 26611536

Schögler A, Muster RJ, Kieninger E, Casaulta C, Tapparel C, Jung A, Moeller A, Geiser T, Regamey N, Alves MP. Vitamin D represses rhinovirus replication in cystic fibrosis cells by inducing LL-37. Eur Respir J. 2016 Feb;47(2):520-30. PMID: 26585423

Korten I, Mika M, Klenja S, Kieninger E, Mack I, Barbani MT, Gorgievski M, Frey U, Hilty M, Latzin P. Interactions of Respiratory Viruses and the Nasal Microbiota during the First Year of Life in Healthy Infants. mSphere. 2016 Nov 23;1(6). PMID: 27904883

Korten I, Ramsey K, Latzin P. Air pollution during pregnancy and lung development in the child. Paediatr Respir Rev. 2016 Aug 19. PMID: 27665510

Pusterla O, Bauman G, Wielpütz MO, Nyilas S, Latzin P, Heussel CP, Bieri O. Rapid 3D in vivo 1H human lung respiratory imaging at 1.5 T using ultra-fast balanced steady-state free precession. Magn Reson Med. 2016 Oct 23. PMID: 27774645

Yammine S, Summermatter S, Singer F, Lauener R, Latzin P. Feasibility of nitrogen multiple-breath washout in inexperienced children younger than 7 years. Pediatr Pulmonol. 2016 Nov;51(11):1183-1190. PMID: 27132707

Jost K, Egger B, Kieninger E, Singer F, Frey U, Latzin P. Changes in minute ventilation after exposure to 4% sulfur hexafluoride (SF6 ) in infants. Pediatr Pulmonol. 2016 Sep 2. PMID: 27589241

Usemann J, Fuchs O, Anagnostopoulou P, Korten I, Gorlanova O, Röösli M, Latzin P, Frey U. Predictive value of exhaled nitric oxide in healthy infants for asthma at school age. Eur Respir J. 2016 Sep;48(3):925-8. PMID: 27390276

Boeck L, Gensmer A, Nyilas S, Stieltjes B, Re TJ, Tamm M, Latzin P, Stolz D. Single-Breath Washout Tests to Assess Small Airway Disease in COPD. Chest. 2016 Nov;150(5):1091-1100. PMID: 27256720

Mack I, Kieninger E, Cangiano G, Tapparel C, Kuehni C, Spycher B, Kaiser L, Frey U, Regamey N, Latzin P. Rhinovirus Infections and Associated Respiratory Morbidity in Infants: A Prospective Cohort Study. Pediatr Infect Dis J. 2016 Oct;35(10):1069-74. PMID: 27254029

Nyilas S, Singer F, Kumar N, Yammine S, Meier-Girard D, Koerner-Rettberg C, Casaulta C, Frey U, Latzin P. Physiological phenotyping of pediatric chronic obstructive airway diseases. J Appl Physiol (1985). 2016 Jul 1;121(1):324-32. PMID: 27231309

Proietti E, Delgado-Eckert E, Vienneau D, Stern G, Tsai MY, Latzin P, Frey U, Röösli M. Air pollution modelling for birth cohorts: a time-space regression model. Environ Health. 2016 May 25;15(1):61. PMID: 27225793

Egger B, Jost K, Anagnostopoulou P, Yammine S, Singer F, Casaulta C, Frey U, Latzin P. Lung clearance index and moment ratios at different cut-off values in infant multiple-breath washout measurements. Pediatr Pulmonol. 2016 Dec;51(12):1373-1381. PMID: 27214661

Usemann J, Frey U, Mack I, Schmidt A, Gorlanova O, Röösli M, Hartl D, Latzin P. CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development. BMC Pulm Med. 2016 May 18;16(1):81. PMID: 27193312

Mika M, Korten I, Qi W, Regamey N, Frey U, Casaulta C, Latzin P, Hilty M; SCILD study group. The nasal microbiota in infants with cystic fibrosis in the first year of life: a prospective cohort study. Lancet Respir Med. 2016 Aug;4(8):627-35. PMID: 27180018

Yammine S, Nyilas S, Casaulta C, Schibli S, Latzin P, Sokollik C. Function and Ventilation of Large and Small Airways in Children and Adolescents with Inflammatory Bowel Disease. Inflamm Bowel Dis. 2016 Aug;22(8):1915-22. PMID: 27120569

Gorlanova O, Thalmann S, Proietti E, Stern G, Latzin P, Kühni C, Röösli M, Frey U. Effects of Breastfeeding on Respiratory Symptoms in Infancy. J Pediatr. 2016 Jul;174:111-117.e5. PMID: 27063808

Jost K, Lenherr N, Singer F, Schulzke SM, Frey U, Latzin P, Yammine S. Changes in breathing pattern upon 100% oxygen in children at early school age. Respir Physiol Neurobiol. 2016 Jul;228:9-15. PMID: 26970571

Anagnostopoulou P, Egger B, Lurà M, Usemann J, Schmidt A, Gorlanova O, Korten I, Roos M, Frey U, Latzin P. Multiple breath washout analysis in infants: quality assessment and recommendations for improvement. Physiol Meas. 2016 Mar;37(3):L1-L15. PMID: 26849570

Yammine S, Singer F, Latzin P. CFTR modulation for young children with cystic fibrosis. Lancet Respir Med. 2016 Feb;4(2):84-5. PMID: 26803278

Singer F, Casaulta C, Latzin P. How to Monitor Early Cystic Fibrosis Lung Disease. By Multiple-Breath Washout, Chest Computed Tomography, or Both? Am J Respir Crit Care Med. 2016 Jan 1;193(1):7-8. PMID: 26720785

Loza MJ, Djukanovic R, Chung KF, Horowitz D, Ma K, Branigan P, Barnathan ES, Susulic VS, Silkoff PE, Sterk PJ, Baribaud F; ADEPT (Airways Disease Endotyping for Personalized Therapeutics) and U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome Consortium) investigators. Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study. Respir Res. 2016 Dec 15;17(1):165. PMID: 27978840
Collaborators (220)
Adcock I, Adriaens N, Ahmed H, Aliprantis A, Alving K, Auffray C, Badorrek P, Bakke P, Balgoma D, Bansal AT, Barber C, Baribaud F, Bautmans A, Behndig AF, Bel E, Beleta J, Berglind A, Berton A, Bigler J, Bisgaard H, Bochenek G, Boedigheimer MJ, Bøonnelykke K, Brandsma J, Braun A, Brinkman P, Burg D, Campagna D, Carayannopoulos L, Caruso M, da Purificação RJ, Chaiboonchoe A, Chaleckis R, Chanez P, Chung KF, Coleman C, Compton C, Corfield J, D'Amico A, Dahlen B, Dahlén SE, De Alba J, de Boer P, De Lepeleire I, De Meulder B, Dekker T, Delin I, Dennison P, Dijkhuis A, Djukanovic R, Draper A, Edwards J, Emma R, Ericsson M, Erpenbeck V, Erzen D, Fichtner K, Fitch N, Fleming LJ, Flood B, Fowler SJ, Frey U, Gahlemann M, Galffy G, Gallart H, Garrett T, Geiser T, Gent J, Gerhardsson VM, Gibeon D, Gomez C, Gove K, Gozzard N, Guo YK, Hashimoto S, Haughney J, Hedlin G, Hekking PP, Henriksson E, Hewitt L, Higgenbottam T, Hoda U, Hohlfeld J, Holweg C, Horvath I, Howarth P, Hu R, Hu S, Hu X, Hudson V, James AJ, Kamphuis J, Kennington EJ, Kerry D, Klüglich M, Knobel H, Knowles R, Knox A, Kolmert J, Konradsen J, Kots M, Krueger L, Krug N, Kuo S, Kupczyk M, Lambrecht B, Lantz AS, Larsson L, Lazarinis N, Lefaudeux D, Lone-Latif S, Loza MJ, Lutter R, Marouzet L, Martin J, Masefield S, Mathon C, Matthews JG, Mazein A, Meah S, Meiser A, Menzies-Gow A, Metcalf L, Middelveld R, Mikus M, Miralpeix M, Monk P, Montuschi P, Mores N, Murray CS, Musial J, Myles D, Naz S, Nething K, Nicholas B, Nihlen U, Nilsson P, Nordlund B, Östling J, Pacino A, Pahus L, Palkonen S, Pandis I, Pavlidis S, Pennazza G, Petrén A, Pink S, Postle A, Powel P, Rahman-Amin M, Rao N, Ravanetti L, Ray E, Reinke S, Reynolds L, Riemann K, Riley J, Robberechts M, Roberts A, Roberts G, Rossios C, Rowe A, Russell K, Rutgers M, Sandström T, Santini G, Santoninco M, Schoelch C, Schofield JP, Seibold W, Shaw DE, Sigmund R, Singer F, Sjödin M, Skipp PJ, Smids B, Smith C, Smith J, Smith KM, Söderman P, Sogbesan A, Sousa AR, Staykova D, Sterk PJ, Strandberg K, Sun K, Supple D, Szentkereszty M, Tamasi L, Tariq K, Thörngren JO, Thornton B, Thorsen J, Valente S, van AW, van de Pol M, van DK, van GM, Versnel J, Vestbo J, Vink A, Vissing N, von GC, Wagener A, Wagers S, Wald F, Walker S, Ward J, Weiszhart Z, Wetzel K, Wheelock CE, Wiegman C, Williams S, Wilson SJ, Woodcock A, Yang X, Yeyasingham E, Yu W, Zetterquist W, Zwinderman K.

Lefaudeux D, De Meulder B, Loza MJ, Peffer N, Rowe A, Baribaud F, Bansal AT, Lutter R, Sousa AR, Corfield J, Pandis I, Bakke PS, Caruso M, Chanez P, Dahlén SE, Fleming LJ, Fowler SJ, Horvath I, Krug N, Montuschi P, Sanak M, Sandstrom T, Shaw DE, Singer F, Sterk PJ, Roberts G, Adcock IM, Djukanovic R, Auffray C, Chung KF; U-BIOPRED Study Group. U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics. J Allergy Clin Immunol. 2016 Oct 20. PMID: 27773852
Collaborators (193)
Adriaens N, Ahmed H, Aliprantis A, Alving K, Badorek P, Balgoma D, Barber C, Bautmans A, Behndig AF, Bel E, Beleta J, Berglind A, Berton A, Bigler J, Bisgaard H, Bochenek G, Boedigheimer MJ, Bøonnelykke K, Brandsma J, Braun A, Brinkman P, Burg D, Campagna D, Carayannopoulos L, Carvalho da Purfição Rocha JP, Chaiboonchoe A, Chaleckis R, Coleman C, Compton C, D'Amico A, Dahlén B, De Alba J, de Boer P, De Lepeleire I, Dekker T, Delin I, Dennison P, Dijkhuis A, Draper A, Edwards J, Emma R, Ericsson M, Erpenbeck V, Erzen D, Faulenbach C, Fichtner K, Fitch N, Flood B, Frey U, Gahlemann M, Galffy G, Gallart H, Garret T, Geiser T, Gent J, Gerhardsson de Verdier M, Gibeon D, Gomez C, Gove K, Gozzard N, Guo YK, Hashimoto S, Haughney J, Hedlin G, Hekking PP, Henriksson E, Hewitt L, Higgenbottam T, Hoda U, Hohlfeld J, Holweg C, Howarth P, Hu R, Hu S, Hu X, Hudson V, James AJ, Kamphuis J, Kennington EJ, Kerry D, Klüglich M, Knobel H, Knowles R, Knox A, Kolmert J, Konradsen J, Kots M, Krueger L, Kuo S, Kupczyk M, Lambrecht B, Lantz AS, Larsson L, Lazarinis N, Lone-Satif S, Marouzet L, Martin J, Masefield S, Mathon C, Matthews JG, Mazein A, Meah S, Maiser A, Menzies-Gow A, Metcalf L, Middelveld R, Mikus M, Miralpeix M, Monk P, Mores N, Murray CS, Musial J, Myles D, Naz S, Nething K, Nicholas B, Nihlen U, Nilsson P, Nordlund B, Östling J, Pacino A, Pahus L, Palkonnen S, Pavlidis S, Pennazza G, Petrén A, Pink S, Postle A, Powel P, Rahman-Amin M, Rao N, Ravanetti L, Ray E, Reinke S, Reynolds L, Riemann K, Riley J, Robberechts M, Roberts A, Rossios C, Russell K, Rutgers M, Santini G, Sentoninco M, Schoelch C, Schofield JP, Seibold W, Sigmund R, Sjödin M, Skipp PJ, Smids B, Smith C, Smith J, Smith KM, Söderman P, Sogbesan A, Staykova D, Strandberg K, Sun K, Supple D, Szentkereszty M, Tamasi L, Tariq K, Thörngren JO, Thornton B, Thorsen J, Valente S, van Aalderenm W, van de Pol M, van Drunen K, van Geest M, Versnel J, Vestbo J, Vink A, Vissing N, von Garnier C, Wagerner A, Wagers S, Wald F, Walker S, Ward J, Weiszhart Z, Wetzel K, Wheelock CE, Wiegman C, Williams S, Wilson SJ, Woosdcock A, Yang X, Yeyashingham E, Yu W, Zetterquist W, Zwinderman K.

Yammine S, Schmidt A, Sutter O, Fouzas S, Singer F, Frey U, Latzin P. Functional evidence for continued alveolarisation in former preterms at school age? Eur Respir J. 2016 Jan;47(1):147-55. PMID: 26493788

2015

Yammine S, Lenherr N, Nyilas S, Singer F, Latzin P. Last Word on Viewpoint: Using the same cut-off for sulfur hexafluoride and nitrogen multiple-breath washout may not be appropriate. J Appl Physiol (1985). 2015 Dec 15; 119(12):1515.

Yammine S, Schmidt A, Sutter O, Fouzas S, Singer F, Frey U, Latzin P. Functional evidence for continued alveolarisation in former preterms at school age? Eur Respir J. 2016 Jan;47(1):147-55.

Shaw DE, Sousa AR, Fowler SJ, Fleming LJ, Roberts G, Corfield J, Pandis I, Bansal AT, Bel EH, Auffray C, Compton CH, Bisgaard H, Bucchioni E, Caruso M, Chanez P, Dahlén B, Dahlen SE, Dyson K, Frey U, Geiser T, Gerhardsson de Verdier M, Gibeon D, Guo YK, Hashimoto S, Hedlin G, Jeyasingham E, Hekking PP, Higenbottam T, Horváth I, Knox AJ, Krug N, Erpenbeck VJ, Larsson LX, Lazarinis N, Matthews JG, Middelveld R, Montuschi P, Musial J, Myles D, Pahus L, Sandström T, Seibold W, Singer F, Strandberg K, Vestbo J, Vissing N, von Garnier C, Adcock IM, Wagers S, Rowe A, Howarth P, Wagener AH, Djukanovic R, Sterk PJ, Chung KF; U-BIOPRED Study Group. Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort. Eur Respir J. 2015 Nov;46(5):1308-21.

Usemann J, Korten I, Latzin P. A big step forward in understanding global differences in respiratory health: first lung function data in African infants. Respirology. 2015 Oct;20(7):1006-7.

Anagnostopoulou P, Yammine S, Schmidt A, Korten I, Kieninger E, Mack I, Trachsel D, Hafen G, Moeller A, Casaulta C, Latzin P. False normal Lung Clearance Index in infants with cystic fibrosis due to software algorithms. Pediatr Pulmonol. 2015 Oct;50(10):970-7.

Summermatter S, Singer F, Latzin P, Yammine S. Impact of Software Settings on Multiple-Breath Washout Outcomes. PLoS One. 2015 Jul 13;10(7):e0132250.

Sonneveld N, Stanojevic S, Amin R, Aurora P, Davies J, Elborn JS, Horsley A, Latzin P, O'Neill K, Robinson P, Scrase E, Selvadurai H, Subbarao P, Welsh L, Yammine S, Ratjen F. Lung clearance index in cystic fibrosis subjects treated for pulmonary exacerbations. Eur Respir J. 2015 Oct;46(4):1055-64.

Yammine S, Lenherr N, Nyilas S, Singer F, Latzin P. Using the same cut-off for sulfur hexafluoride and nitrogen multiple-breath washout may not be appropriate. J Appl Physiol (1985). 2015 Dec 15;119(12):1510-2.

Müller L, Mack I, Tapparel C, Kaiser L, Alves MP, Kieninger E, Frey U, Regamey N, Latzin P. Human Rhinovirus Types and Association with Respiratory Symptoms During the First Year of Life. Pediatr Infect Dis J. 2015 Aug;34(8):907-9.

Nyilas S, Schlegtendal A, Yammine S, Casaulta C, Latzin P, Koerner-Rettberg C. Further evidence for an association between LCI and FEV1 in patients with PCD. Thorax. 2015 Sep;70(9):896.

Bigler A, Yammine S, Singer F, Riedel T, Latzin P. Feasibility of automated slope III and Scond analysis in children. Pediatr Pulmonol. 2015 Aug;50(8):805-13.

Schmidt A, Yammine S, Proietti E, Frey U, Latzin P, Riedel T, Singer F. Validation of multiple-breath washout equipment for infants and young children. Pediatr Pulmonol. 2015 Jun;50(6):607-14.

den Dekker HT, Sonnenschein-van der Voort AM, de Jongste JC, Anessi-Maesano I, Arshad SH, Barros H, Beardsmore CS, Bisgaard H, Phar SC, Craig L, Devereux G, van der Ent CK, Esplugues A, Fantini MP, Flexeder C, Frey U, Forastiere F, Gehring U, Gori D, van der Gugten AC, Henderson AJ, Heude B, Ibarluzea J, Inskip HM, Keil T, Kogevinas M, Kreiner-Møller E, Kuehni CE, Lau S, Mélen E, Mommers M, Morales E, Penders J, Pike KC, Porta D, Reiss IK, Roberts G, Schmidt A, Schultz ES, Schulz H, Sunyer J, Torrent M, Vassilaki M, Wijga AH, Zabaleta C, Jaddoe VW, Duijts L. Early growth characteristics and the risk of reduced lung function and asthma: A meta-analysis of 25,000 children. J Allergy Clin Immunol. 2015 Nov 5. pii: S0091-6749(15)01361-5.

Petrus NC, Thamrin C, Fuchs O, Frey U. Accuracy of tidal breathing measurement of FloRight compared to an ultrasonic flowmeter in infants. Pediatr Pulmonol. 2015 Apr;50(4):380-8.

Schögler A, Stokes AB, Casaulta C, Regamey N, Edwards MR, Johnston SL, Jung A, Moeller A, Geiser T, Alves MP. Interferon response of the cystic fibrosis bronchial epithelium to major and minor group rhinovirus infection. J Cyst Fibros. 2015 Nov 21. pii: S1569-1993(15)00257-X.

Alves MP, Schögler A, Ebener S, Vielle NJ, Casaulta C, Jung A, Moeller A, Geiser T, Regamey N. Comparison of innate immune responses towards rhinovirus infection of primary nasal and bronchial epithelial cells. Respirology. 2016 Feb;21(2):304-12.

Schögler A, Muster RJ, Kieninger E, Casaulta C, Tapparel C, Jung A, Moeller A, Geiser T, Regamey N, Alves MP. Vitamin D represses rhinovirus replication in cystic fibrosis cells by inducing LL-37. Eur Respir J. 2016 Feb;47(2):520-30.

Schögler A, Kopf BS, Edwards MR, Johnston SL, Casaulta C, Kieninger E, Jung A, Moeller A, Geiser T, Regamey N, Alves MP. Novel antiviral properties of azithromycin in cystic fibrosis airway epithelial cells. Eur Respir J. 2015 Feb;45(2):428-39.

Steinmann M, Abbas C, Singer F, Casaulta C, Regamey N, Haffner D, Fischer DC, Simonetti GD. Arterial stiffness is increased in asthmatic children. Eur J Pediatr. 2015 Apr;174(4):519-23.

Mika M, Mack I, Korten I, Qi W, Aebi S, Frey U, Latzin P, Hilty M. Dynamics of the nasal microbiota in infancy: a prospective cohort study. J Allergy Clin Immunol. 2015 Apr;135(4):905-12.e11.

Stanojevic S, Jensen R, Sundaralingam D, Salazar JG, Yammine S, Singer F, Latzin P, Amin R, Subbarao P, Gustafsson P, Ratjen F. Alternative outcomes for the multiple breath washout in children with CF. J Cyst Fibros. 2015 Jul;14(4):490-6.

Frey U, Latzin P, Usemann J, Maccora J, Zumsteg U, Kriemler S. Asthma and obesity in children: current evidence and potential systems biology approaches.Allergy. 2015 Jan;70(1):26-40.

2014

Singer F, Yammine S, Schmidt A, Proietti E, Kieninger E, Barben J, Casaulta C, Regamey N, Gustafsson P, Frey U, Latzin P. Ventilatory response to nitrogen multiple-breath washout in infants. Pediatr Pulmonol. 2014, Apr;49(4):342-7.

Singer F, Abbas C, Yammine S, Casaulta C, Frey U, Latzin P. Abnormal small airways function in children with mild asthma. Chest. 2014, Mar 1;145(3):492-9.

Yammine S, Singer F, Gustafsson P, Latzin P. Impact of different breathing protocols on multiple-breath washout outcomes in children. J Cyst Fibros. 2014, Mar;13(2):190-7.

Yammine S, Bigler A, Casaulta C, Singer F, Latzin P. Reasons for heterogeneous change in LCI in children with cystic fibrosis after antibiotic treatment. Thorax. 2014, Feb;69(2):183.

Bigler A, Yammine S, Singer F, Riedel T, Latzin P. Feasibility of automated slope III and Scond analysis in children. Pediatr Pulmonol. 2014 Jul 23. [Epub ahead of print]

Stahl M, Joachim C, Blessing K, Hämmerling S, Sommerburg O, Latzin P, Mall MA. Multiple breath washout is feasible in the clinical setting and detects abnormal lung function in infants and young children with cystic fibrosis. Respiration. 2014;87(5):357-63.

Proietti E, Riedel T, Fuchs O, Pramana I, Singer F, Schmidt A, Kuehni C, Latzin P, Frey U. Can infant lung function predict respiratory morbidity during the first year of life in preterm infants? Eur Respir J. 2014 Jun;43(6):1642-51.

Schmidt A, Yammine S, Proietti E, Frey U, Latzin P, Riedel T, Singer F. Validation of multiple-breath washout equipment for infants and young children. Pediatr Pulmonol. 2014 Feb 25. [Epub ahead of print]

Fouzas S, Häcki C, Latzin P, Proietti E, Schulzke S, Frey U, Delgado-Eckert E. Volumetric Capnography in Infants with Bronchopulmonary Dysplasia. J Pediatr. 2014, Feb;164(2):283-8.e1-3.

Cangiano G, Proietti E, Kronig MN, Kieninger E, Sadeghi CD, Gorgievski M, Barbani MT, Midulla F, Tapparel C, Kaiser L, Alves MP, Regamey N. Lactate dehydrogenase concentration in nasal wash fluid indicates severity of rhinovirus-induced wheezy bronchitis in preschool children. Pediatr Infect Dis J. 2014 Dec;33(12):1285-7

Schögler A, Kopf BS, Edwards MR, Johnston SL, Casaulta C, Kieninger E, Jung A, Moeller A, Geiser T, Regamey N, Alves MP. Novel antiviral properties of azithromycin in cystic fibrosis airway epithelial cells. Eur Respir J. 2014 Oct 30. [Epub ahead of print]

Steinmann M, Abbas C, Singer F, Casaulta C, Regamey N, Haffner D, Fischer DC, Simonetti GD. Arterial stiffness is increased in asthmatic children. Eur J Pediatr. 2014 Sep 25. [Epub ahead of print]

Stokes AB, Kieninger E, Schögler A, Kopf BS, Casaulta C, Geiser T, Regamey N, Alves MP. Comparison of three different brushing techniques to isolate and culture primary nasal epithelial cells from human subjects. Exp Lung Res. 2014 Sep;40(7):327-32.

Renk H, Regamey N, Hartl D. Influenza A(H1N1)pdm09 and cystic fibrosis lung disease: a systematic meta-analysis. PLoS One. 2014 Jan 10;9(1):e78583.

Latzin P, Thompson B. Double tracer gas single-breath washout: promising for clinics or just a toy for research? Eur Respir J. 2014 Nov;44(5):1113-5.

Latzin P, Thompson B. Validation of multiple-breath washout equipment: from bench to clinic and possible pitfalls.Respiration. 2014;87(6):456-8

2013

Singer F, Abbas C, Yammine S, Casaulta C, Frey U, Latzin P. Abnormal small airways function in children with mild asthma. Chest. 2013 Oct 3. doi: 10.1378/chest.13-0784. [Epub ahead of print]

Yammine S, Singer F, Gustafsson P, Latzin P. Impact of different breathing protocols on multiple-breath washout outcomes in children. J Cyst Fibros. 2013 Sep 25. doi: 10.1016/j.jcf.2013.08.010. [Epub ahead of print]

Yammine S, Bigler A, Casaulta C, Singer F, Latzin P. Reasons for heterogeneous change in LCI in children with cystic fibrosis after antibiotic treatment. Thorax. 2013 Aug 29. doi: 10.1136/thoraxjnl-2013-204283. [Epub ahead of print]

Singer F, Yammine S, Schmidt A, Proietti E, Kieninger E, Barben J, Casaulta C, Regamey N, Gustafsson P, Frey U, Latzin P. Ventilatory response to nitrogen multiple-breath washout in infants. Pediatr Pulmonol. 2013 Jul 12. doi: 10.1002/ppul.22841. [Epub ahead of print]

Singer S, Kieninger E, Abbas C, Yammine S, Fuchs O, Proietti E, Regamey N, Casaulta C, Frey U, Latzin P. Practicability of nitrogen multiple-breath washout measurements in a pediatric cystic fibrosis outpatient setting. Pediatr Pulmonol. 2013 Aug;48(8):739-46. doi: 10.1002/ppul.22651.

Singer F, Stern G, Thamrin C, Abbas C, Casaulta C, Frey U, Latzin P. A new double-tracer gas single-breath washout to assess early cystic fibrosis lung disease. Eur Respir J. 2013 Mar;41(3):507-22.

Kieninger E, Singer F, Tapparel C, Alves MP, Latzin P, Tan HL, Bossley C, Casaulta C, Bush A, Davies JC, Kaiser L, Regamey N. High rhinovirus burden in lower airways of children with cystic fibrosis. Chest. 2013 Mar;143(3):782-90. 

Stern G, Latzin P, Röösli M, Fuchs O, Proietti E, Kuehni C, Frey U. A prospective study of the impact of air pollution on respiratory symptoms and infections in infants. Am J Respir Crit Care Med. 2013 Jun 15;187(12):1341-8. doi: 10.1164/rccm.201211-2008OC. 

Abbas C, Singer F, Yammine S, Casaulta C, Latzin P. Treatment response of airway clearance assessed by single-breath washout in children with cystic fibrosis. J Cyst Fibros. 2013 Dec;12(6):567-74. doi: 10.1016/j.jcf.2013.05.010.

Waldmeier S, Grunt S, Delgado-Eckert E, Latzin P, Steinlin M, Fuhrer K, Frey U. Correlation properties of spontaneous motor activity in healthy infants: a new computer-assisted method to evaluate neurological maturation. Exp Brain Res. 2013 Jun;227(4):433-46.

Singer F, Luchsinger I, Inci D, Knauer N, Latzin P, Wildhaber JH, Moeller A. Exhaled nitric oxide in symptomatic children at preschool age predicts later asthma. Allergy. 2013 Apr;68(4):531-8.

Yammine S, Singer F, Abbas C, Roos M, Latzin P. Multiple-breath washout measurements can be significantly shortened in children. Thorax. 2013 Jun;68(6):586-7. doi: 10.1136/thoraxjnl-2012-202345.

Navarini S, Latzin P, Kadner A, Carrel T, Hutter D. Giant Cardiac Fibroma: An Unusual Cause of Failure to Thrive. Pediatr Cardiol. 2013 Jun;34(5):1264-6.

Robinson PD, Latzin P, Verbanck S, Hall GL, Horsley A, Gappa M, Thamrin C, Arets HG, Aurora P, Fuchs SI, King GG, Lum S, Macleod K, Paiva M, Pillow JJ, Ranganathan S, Ratjen F, Singer F, Sonnappa S, Stocks J, Subbarao P, Thompson BR, Gustafsson PM. Consensus statement for inert gas washout measurement using multiple- and single- breath tests. Eur Respir J. 2013 Mar;41(3):507-22.

Proietti E, Röösli M, Frey U, Latzin P. Air Pollution During Pregnancy and Neonatal Outcome: A Review. J Aerosol Med Pulm Drug Deliv. 2013 Feb;26(1):9-23.

Kieninger E, Fuchs O, Latzin P, Frey U, Regamey N. Rhinovirus infections in infancy and early childhood. Eur Respir J. 2013 Feb;41(2):443-52.

MacNeill SJ, Sozanska B, Danielewicz H, Debinska A, Kosmeda A, Boznanski A, Illi S, Depner M, Strunz-Lehner C, Waser M, Büchele G, Horak E, Genuneit J, Heederik D, Braun-Fahrländer C, von Mutius E, Cullinan P; GABRIELA study group. Asthma and allergies: is the farming environment (still) protective in Poland? The GABRIEL Advanced Studies. Allergy. 2013 Jun;68(6):771-9.

Stöcklin L, Loss G, von Mutius E, Weber J, Genuneit J, Horak E, Sozanska B, Danielewicz H, Cullinan P, Heederick D, Braun-Fahrländer C; GABRIEL study group. Health-related quality of life in rural children living in four European countries: the GABRIEL study. Int J Public Health. 2013 Jun;58(3):355-66.

Fouzas S, Häcki C, Latzin P, Proietti E, Schulzke S, Frey U, Delgado-Eckert E. Volumetric Capnography in Infants with Bronchopulmonary Dysplasia. J Pediatr. 2013 Oct 22. doi: 10.1016/j.jpeds.2013.09.034. [Epub ahead of print]

2012

Yammine S, Singer F, Abbas C, Roos M, Latzin P. Multiple-breath washout measurements can be significantly shortened in children. Thorax. 2012 Oct 31. [Epub ahead of print]

Edwards MR*, Regamey N*, Vareille M, Kieninger E, Gupta A, Shoemark A, Saglani S, Sykes A, Macintyre J, Davies JC, Bossley C, Bush A, Johnston SL. Impaired innate interferon induction in severe therapy resistant asthmatic children. Mucosal Immunology 2012 Dec 5 (Epub ahead of print) *shared first co-authorship

Kieninger E, Singer F, Tapparel C, Alves PA, Latzin P, Tan HL, Bossley C, Casaulta C, Bush A, Davies JC, Kaiser L, Regamey N. High rhinovirus burden in lower airways of children with cystic fibrosis. Chest 2012 Sep 24 (Epub ahead of print)

Singer S, Kieninger E, Abbas C, Yammine S, Fuchs O, Proietti E, Regamey N, Casaulta C, Frey U, Latzin P. Practicability of nitrogen multiple-breath washout measurements in a pediatric cystic fibrosis outpatient setting. Pediatr Pulmonol. 2012 Aug 8. [Epub ahead of print]

Fuchs O, Genuneit J, Latzin P, Büchele G, Horak E, Loss G, Sozanska B, Weber J, Boznanski A, Heederik D, Braun-Fahrländer C, Frey U, von Mutius E; GABRIELA Study Group. Farming environments and childhood atopy, wheeze, lung function, and exhaled nitric oxide. J Allergy Clin Immunol. 2012 Aug;130(2):382-388.e6. Epub 2012 Jun 28.

Buehler T, Steinmann M, Singer F, Regamey N, Casaulta C, Schoeni MH, Simonetti GD. Increased Arterial Stiffness in Children with Cystic Fibrosis [Research Letter]. Eur Respir J 2012 Jun; 39(6):1536-7

Vareille M, Kieninger E, Alves M, Kopf BS, Moeller A, Geiser T, Johnston SL, Edwards MR, Regamey N. Impaired type I and III interferon induction and rhinovirus control in human cystic fibrosis airway epithelial cells. Thorax 2012 Jun;67(6):517-25

Singer F, Stern G, Thamrin C, Abbas C, Casaulta C, Frey U, Latzin P. A new double-tracer gas single-breath washout to assess early cystic fibrosis lung disease. Eur Respir J. 2012. Epub May 17.

Singer F, Houltz B, Latzin P, Robinson P, Gustafsson P. A realistic validation study of a new nitrogen multiple-breath washout system. PLoS One. 2012;7(4):e36083. Epub 2012 Apr 27.

Fuchs O, Latzin P, Singer F, Petrus N, Proietti E, Kieninger E, Casaulta C, Frey U. Comparison of online single-breath vs. online multiple-breath exhaled nitric oxide in school-age children. Pediatr Res. 2012 May;71(5):605-11. Epub 2012 Feb 9.

Regamey N, Tsartsali L, Hilliard TN, Fuchs O, Tan HL, Zhu J, Qiu YS, Alton E, Jeffery P, Bush A, Davies JC. Distinct patterns of inflammation in the airway lumen and bronchial mucosa of children with cystic fibrosis. Thorax 2012 Feb;67(2):170-6

Kieninger E, Vareille M, Kopf BS, Blank F, Alves M, Gisler F, Latzin P, Casaulta C, Geiser T, Johnston SL, Edwards M, Regamey N. Lack of an exaggerated inflammatory response upon virus infection in cystic fibrosis. Eur Respir J 2012 Feb;39(2):297-304

Fleming L, Tsartsali L, Wilson N, Regamey N, Bush A. Sputum inflammatory phenotypes are not stable in children with asthma. Thorax 2012 Aug; 67(8):675-81

Illi S, Depner M, Genuneit J, Horak E, Loss G, Strunz-Lehner C, Büchele G, Boznanski A, Danielewicz H, Cullinan P, Heederik D, Braun-Fahrländer C, von Mutius E; GABRIELA Study Group. Protection from childhood asthma and allergy in Alpine farm environments-the GABRIEL Advanced Studies. J Allergy Clin Immunol. 2012 Jun;129(6):1470-7.e6. Epub 2012 Apr 24

Bossley C, Fleming L, Gupta A, Regamey N, Frith J, Oates T, Tsartsali L, Lloyd CM, Bush A, Saglani S. Paediatric severe asthma is characterised by eosinophilia and remodelling without Th2 cytokines. Journal of Allergy and Clinical Immunology 2012 April; (4):974-82

Fleming L, Wilson N, Regamey N, Bush A. Use of sputum eosinophil counts to guide management in children with severe asthma. Thorax 2012 March;67(3):193-8

Navarini S, Latzin P, Kadner A, Carrel T, Hutter D. Giant Cardiac Fibroma: An Unusual Cause of Failure to Thrive. Pediatr Cardiol. 2012 May 30.

Marchand M, Pfammatter JP, Regamey N. Pulmonary hypertension and macrocephaly in a newborn. Respiration 2012 Feb; 83(5):421-2

Tan HL, Regamey N, Brown S, Bush A, Lloyd CM, Davies JC. IL-17 and neutrophils in cystic fibrosis. Am J Respir Crit Care Med 2012 Jan 1;185(1):109-10

Regamey N, Jeffery PK, Alton E, Bush A, Davies JC. Should bronchoscopy be advocated to study airway remodeling and inflammation in adults with cystic fibrosis? Thorax 2012;67:177

Kieninger E, Fuchs O, Latzin P, FreyU, Regamey N. Rhinovirus infections in infancy and early childhood. Eur Respir J 2012.  Epub Jun 27

Kieninger E, Regamey N. Rhinoviruses – markers of or causative for recurrent wheeze and asthma? Eur Respir J 2012 Feb;39(2):238-9

Proietti E, Röösli M, Frey U, Latzin P. Air Pollution During Pregnancy and Neonatal Outcome: A Review. J Aerosol Med Pulm Drug Deliv. 2012 Epub Aug 2

2011

Thamrin C, Nydegger R, Stern G, Chanez P, Wenzel SE, Watt RA, FitzPatrick S, Taylor DR, Frey U. Associations between fluctuations in lung function and asthma control in two populations with differing asthma severity. Thorax. 2011 Dec;66(12):1036-42

Stern G, de Jongste J, van der Valk R, Baraldi E, Carraro S, Thamrin C, Frey U. Fluctuation phenotyping based on daily fraction of exhaled nitric oxide values in asthmatic children. J Allergy Clin Immunol. 2011 Aug;128(2):293-300. Epub 2011 Apr 13

Navarini S, Bucher B, Pavlovic M, Pfammatter JP, Casaulta C, Brasch F, Griese M, Regamey N. Pulmonary hypertension presenting with apnea, cyanosis and failure to thrive in a young child. Chest 2011 Oct;140(4):1086-9

Thamrin C, Zindel J, Nydegger R, Reddel HK, Chanez P, Wenzel SE, FitzPatrick S, Watt RA, Suki B, Frey U. Predicting future risk of asthma exacerbations using individual conditional probabilities. J Allergy Clin Immunol. 2011 Jun;127(6):1494-502.e3. Epub 2011 Feb 18.

Kieninger E., Singer F., Fuchs O., Abbas C., Frey U., Regamey N., Casaulta C., Latzin P. Long-term course of lung clearance index between infancy and school-age in cystic fibrosis subjects. J Cyst Fibros. 2011 Dec;10(6):487-90. Epub 2011 Aug 10

Latzin P, Frey U, Armann J, Kieninger E, Fuchs O, Röösli M, Schaub B. Exposure to Moderate Air Pollution during Late Pregnancy and Cord Blood Cytokine Secretion in Healthy Neonates. PLoS One. 2011;6(8):e23130. Epub 2011 Aug 3.

Schlapbach LJ, Aebischer M, Adams M, Natalucci G, Bonhoeffer J, Latzin P, Nelle M, Bucher HU, Latal B. Impact of Sepsis on Neurodevelopmental Outcome in a Swiss National Cohort of Extremely Premature Infants. Pediatrics. 2011 Jul 18. [Epub ahead of print]

Pramana IA, Latzin P, Schlapbach LJ, Hafen G, Kuehni CE, Nelle M, Riedel T, Frey U. Respiratory symptoms in preterm infants: burden of disease in the first year of life. Eur J Med Res. 2011 May 12;16(5):223-30

Singer F, Stern G, Thamrin C, Fuchs O, Riedel T, Gustafsson P, Frey U, Latzin P. Tidal volume single breath washout of two tracer gases - a practical and promising lung function test. PLoS One. 2011 Mar 10;6(3):e17588.

Fuchs O, Latzin P, Kuehni CE, Frey U. Cohort Profile: The Bern Infant Lung Development Cohort. Int J Epidemiol. 2011 Jan 13.

Fuchs O, Latzin P, Thamrin C, Stern G, Frischknecht P, Singer F, Kieninger E, Proietti E, Riedel T, Frey U. Normative data for lung function and exhaled nitric oxide in unsedated healthy infants. Eur Respir J. 2011 May;37(5):1208-16.

Ege MJ et al. and the GABRIELA Transregio 22 Study Group. Exposure to environmental microorganisms and childhood asthma. N Engl J Med. 2011 Feb 24;364(8):701-9.

Ege MJ et al. and the GABRIELA Study Group. Gene-environment interaction for childhood asthma and exposure to farming in Central Europe. J Allergy Clin Immunol. 2011 Jan;127(1):138-44, 144.e1-4.

van der Valk RJ, Baraldi E, Stern G, Frey U, de Jongste JC. Daily exhaled nitric oxide measurements and asthma exacerbations in children. Allergy. Epub 2011 Oct 17.

Hector A., Kormann MS., Mack I., Latzin P., Casaulta C., Kieninger E., Zhou Z., Yildirim AÖ., Bohla A., Rieber N., Kappler M., Koller B., Eber E., Eickmeier O., Zielen S., Eickelberg O., Griese M., Mall MA., Hartl D. The Chitinase-Like Protein YKL-40 Modulates Cystic Fibrosis Lung Disease. PLoS One.2011;6(9):e24399. Epub 2011 Sep 20

Tan HL, Regamey N, Brown S, Bush A, Lloyd CM, Davies JC. The Th17 pathway in cystic fibrosis lung disease. Am J Respir Crit Care Med 2011 Jul 15;184(2):252-8

Loss G et al. and the GABRIELA Study Group. The protective effect of farm milk consumption on childhood asthma and atopy: the GABRIELA study. J Allergy Clin Immunol. 2011 Oct;128(4):766-773.e4. Epub 2011 Aug 27

Genuneit J et al. and the GABRIELA Study Group. The GABRIEL Advanced Surveys: study design, participation and evaluation of bias. Paediatr Perinat Epidemiol. 2011 Sep;25(5):436-47. Epub 2011 Jul 28.

2010

Besson S, Latzin P, Stern G, Strippoli MP, Kuehni C, Roosli M, Frey U. Influence of Atmospheric Parameters and Pollutants on Control of Breathing in Healthy Neonates. Ann Resp Med. Epub Nov 24

Hutten GJ, van Eykern LA, Latzin P, Thamrin C, van Aalderen WM, Frey U. Respiratory muscle activity related to flow and lung volume in preterm infants compared with term infants. Pediatr Res. 2010 Oct; 68 (4): 339-43

Thamrin C, Stern G, Frey U. Fractals for physicians. Paediatr Respir Rev. 2010 Jun; 11 (2): 123-31

Thamrin C, Taylor DR, Jones SL, Suki B, Frey U. Variability of lung function predicts loss of asthma control following withdrawal of inhaled corticosteroid treatment. Thorax. 2010 May; 65 (5): 403-8

Griesenbach U, Soussi S, Larsen M, Casamayor I, Dewar A, Regamey N, Bush A, Shah P, Davies J, Alton E. Quantification of PCL height in human airway biopsies is feasible, but not suitable as a biomarker. Am J Respir Cell Mol Biol 2010 Mar; 44 (3): 309-15

Marcos V, Latzin P, Hector A, Sonanini S, Hoffmann F, Lacher M, Koller B, Bufler P, Nicolai T, Hartl D, Griese M. Expression, regulation and clinical significance of soluble and membrane CD14 receptors in pediatric inflammatory lung diseases. Respir Res. 2010 Mar 19;11 (1): 32

Schindera C, Kraemer AL, Gorgievski-Hrisoho M, Aebi C, Regamey N, Barbani MT. Immunofluorescence versus xTAG Multiplex PCR for the Detection of Respiratory Picornavirus Infections in Children. J Clin Virol 2010; 48 (3): 223-225

Thamrin C, Gangell CL, Kusel MM, Schultz A, Hall GL, Stick SM, Sly PD. Expression of bronchodilator response using forced oscillation technique measurements: absolute versus relative. Letter to Eur Respir J. 2010 Jul; 36 (1): 212

Kieninger E, Regamey N. Targeting inflammation in Cystic Fibrosis. Respiration 2010;79/3:189-90

Kraemer R, Thamrin C. Pulmonary outcome prediction for cystic fibrosis patients. Pediatr Pulmonol. 2010 Dec;45(12):1153-5

Regamey N, Jefferey PK, Alton EWFW, Bush A, Davies JC. Airway remodeling and its relationship to inflammation in cystic fibrosis. Thorax. 2010 Oct 1 (Epub ahead of print)

Regamey N, Moeller A. Paediatric exercise testing. European Respiratory Monograph. 2010 March; 47:291-309

Robinson P, Latzin P, Gustafsson P. Multiple-breath washout. European Respiratory Monograph. 2010 Mar;47:87-105

Singer F, Latzin P. Exhaled nitric oxide in infants: a marker of inflammation? European Respiratory Monograph. 2010 Sep;49:56-71

Thamrin C, Stern G. New methods: what do they tell us? Fluctuation analysis of lung function European Respiratory Society Monograph 2010; 47: 310-324

Vareille M, Kieninger E, Edwards MR, Regamey N. The airway epithelium: soldier in the fight against respiratory viruses. Clin Microbiol Rev 2011 Jan; 24(1):210-29

2009

Regamey N, Balfour-Lynn I, Rosenthal M, Hogg C, Bush A, Davies JC. Time required to obtain endobronchial biopsies in children during fibreoptic bronchoscopy. Pediatr Pulmonol 2009;44(1):76-9

Schlapbach LJ, Latzin P, Regamey N, Kuehni CE, Zwahlen M, Casaulta C, Aebi C, Frey U. Mannose-binding lectin cord blood levels and respiratory symptoms during infancy - a prospective birth cohort study. Pediatr Allergy Immunol 2009 May; 20(3):219-26

Riedel T, Kyburz M, Latzin P, Thamrin C, Frey U. Regional and overall ventilation inhomogeneities in preterm and term-born infants. Intensive Care Med 2009;35(1):144-151

Kraemer R, Latzin P, Pramana I, Ballinari P, Gallati S, Frey U. Long-term gas exchange characteristics as markers of deterioration in patients with cystic fibrosis. Respir Res. 2009; Nov 12(10):106

Latzin P, Roth S, Thamrin C, Hutten GJ, Pramana I, Kuehni CE, Casaulta C, Nelle M, Riedel T, Frey U. Lung volume, breathing pattern and ventilation inhomogeneity in preterm and term infants. PLoS ONE 2009;4(2):e4635

Latzin P, Roosli M, Huss A, Kuehni CE Frey U. Air pollution during pregnancy and lung function in newborns: A birth cohort study. Eur Respir J. 2009 Mar;33(3):594-603

Stern G, Beel J, Suki B, Silverman M, Westaway J, Cernelc M, Baldwin D, Frey U. Long-range correlations in rectal temperature fluctuations of healthy infants during maturation. PLoS One. 2009 Jul 29;4(7):e6431.

Kraemer R, Latzin P, Pramana I, Ballinari P, Gallati S, Frey U. Long-term gas exchange characteristics as marker of deterioration in patients with cystic fibrosis. Respir Res. 2009 Nov 12;10(1):106

Thamrin C, Stern G, Strippoli MF, Kuehni CE, Suki B, Taylor DR, Frey U. Fluctuation analysis of lung function as a predictor of long-term response to b2-agonists. Eur Respir J 2009;33(3):486-93

Thamrin C, Albu G, Sly PD, Hantos Z. Negative impact of the noseclip on high frequency respiratory impedance measurements (short communication). Respir Physiol Neurobiol 2009;165(1):115-118

Tapparel C, Junier T, Van Belle S, Turin L, Gerlach D, Cordey S, Muhlemann K, Regamey N, Aubert JD, Eigenmann P, Zdobnov E, Kaiser L. Genome Analysis of circulating Picornaviruses Reveals a New Respiratory Enterovirus Genotype and Rhinovirus Recombinant Strains. Emerg Infect Dis 2009 May;15(5):719-26

Tapparel C, Cordey S, Van Belle S, Turin L, Lee WM, Regamey N, Meylan P, Muhlemann K, Gobbini F, Kaiser L. New molecular detection tools adapted to emerging rhinoviruses and enteroviruses. J Clin Microbiol 2009 Jun;47(6):1742-9

Steiner P, Otth M, Casaulta C, Aebi C. Autoantibodies against bactericidal/ permeability-increasing protein (BPI) in children with acute pneumonia. FEMS Immunol Med Microbiol. 2009 Nov;57(2):125-8

Simonetti GD, Casaulta C, Vuissoz JM, Bianchetti MG, Nuoffer JM. Recurrent unexplained episodes of facial cyanosis and shortness of breath in Hunter disease. J Pediatr. 2009 Jul;155(1):144

Thamrin C and Frey U. Complexity and respiratory growth: a developing story. J Appl Physiol 2009;106(3): 753-4

2008

Casaulta C, Stirnimann A, Schoeni MH, Barben J. Sweat test in patients with glucose-6-phosphate-1-dehydrogenase deficiency. Arch Dis Child. 2008 Oct;93(10): 878-9

Hutten GJ, van Eykern LA, Latzin P, Kyburz M, van Aalderen WM, Frey U. Relative impact of intercostal and diaphragmatic muscle activity on tidal flow and lung volume in unsedated neonates. Ped Pulmonol 2008; 43: 882-91

Latzin P, Hartl D, Regamey N, Frey U, Schoeni MH, Casaulta C. TARC as serological marker for allergic bronchopulmonary aspergillosis in cystic fibrosis. Eur Respir J 2008;31(1):36-42. IF 5.3

Regamey N, Kaiser L, Roiha HL, Deffernez C, Kuehni CE, Latzin P, Aebi C, Frey U. Viral Aetiology of Acute Respiratory Infections With Cough in Infancy: A Community-Based Birth Cohort Study. Pediatr Infect Dis J 2008; 27(2): 100-5

Regamey N, Ochs M, Hilliard TN, Mühlfeld C, Cornish N, Fleming L, Saglani S, Alton EWFW, Bush A, Jeffery PK, Davies JC. Increased airway smooth muscle mass in children with asthma, cystic fibrosis, and non-cystic fibrosis bronchiectasis. Am J Respir Crit Care Med 2008;177 :837-843.

Riedel T, Kyburz M, Latzin P, Thamrin C, Frey U. Electrical Impedance Tomography compared to Multiple Breath Washout in preterm and term-born infants. Int Care Med 2008; doi:10. 1007/s00134-008-1299-x

Schlapbach LJ, Latzin P, Regamey N, Kuehni CE, Zwahlen M, Casaulta C, Aebi C, Frey U. MBL levels in cord blood and respiratory symptoms during infancy – a prospective birth cohort study. Ped Allergy Clin Immunol 2008; DOI: 10.1111/j.1399-3038.2008.00782.x

Thamrin C and Frey U. Effect of bacterial filter on measurements of interrupter resistance in preschool and school-aged children. Pediatr Pulm 2008;43: 781-787

Wäffler-Kammermann N, Stauffer Lacorcia R, Wettstein M, Radlinger L, Frey U. A new standardised treadmill walking test requiring low motor skills in children aged from 4 to10 years. Pediatr Pulmonol 2008; 43(2): 187-95

Brand PL, Baraldi E, Bisgaard H, Boner AL, Castro-Rodriguez JA, Custovic A, de Blic J, de Jongste JC, Eber E, Everard ML, Frey U, Gappa M, Garcia-Marcos L, Grigg J, Lenney W, Le Souëf P, McKenzie S, Merkus PJ, Midulla F, Paton JY, Piacentini G, Pohunek P, Rossi GA, Seddon P, Silverman M, Sly PD, Stick S, Valiulis A, van Aalderen WM, Wildhaber JH, Wennergren G, Wilson N, Zivkovic Z, Bush A. Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach. Eur Respir J 2008; 32: 1096-110

Latzin P, Fehling M, Bauernfeind A, Reinhardt D, Kappler M, Griese M. Efficacy and safety of intravenous meropenem and tobramycin versus ceftazidime and tobramycin in cystic fibrosis. J Cyst Fibros. 2008 Mar;7 (2): 142-6

Minocchieri S, Burren JM, Bachmann MA, Stern G, Wildhaber J, Buob S, Schindel R, Kraemer R, Frey U, Nelle M. Development of the Premature Infant Nose Throat - Model (PrINT - Model) - an Upper Airway Replica of a Prema-ture Neonate for the Study of Aerosol Delivery. Pediatr Res. 2008 Aug; 64(2): 141-6

Schneider M, Mühlemann K, Droz S, Couzinet S, Casaulta C, Zimmerli S. Clinical characteristics associated with isolation of small-colony variants of Staphylococcus aureus and Pseudomonas aeruginosa from respiratory secretions of patients with cystic fibrosis. J Clin Microbiol. 2008 May;46(5):1832-4

Tafel O, Latzin P, Paul K, Winter T, Woischnik M, Griese M.Surfactant proteins SP-B and SP-C and their precursors in bronchoalveolar lavages from children with acute and chronic inflammatory airway disease. BMC Pulm Med. 2008 Apr 11; 8: 6

Thamrin C, Albu G, Sly PD, Hantos Z. Negative impact of the noseclip on high frequency respiratory impedance measurements (short communications). Resp Physiol Neurobiol 2009; 165(1): 115-118.

Barben J, Frey U. Obstruktive Atemwegserkrankungen im Kindesalter. Teil 1 Diagnostik, Schweizerisches Medizinisches Forum 2008; 25: 466-470.

Barben J, Frey U.. Obstruktive Atemwegserkrankungen im Kindesalter. Teil 2 Therapie. Schweizerisches Medizinisches Forum 2008; 26: 512-417.

Frey U, Suki B. Complexity in chronic asthma and COPD: implications for risk assessment, disease progression and control. Lancet 2008; 372: 1088–99.

Latzin P, Frey U. Environmental exposure in relation to exhaled nitric oxide in newborns: is it all about timing?, Eur Respir J. 2008 Aug;32(2):252

Latzin P, Thamrin C, Kraemer R. Ventilation inhomogeneities assessed by multibreath washout (MBW) technique. Editorial, Thorax. 2008 Feb;63(2):98

Regamey N, Hilliard TN, Saglani S, Zhu J, Balfour-Lynn IM, Rosenthal M, Jeffery PK, Alton EWFW, Bush A, Davies JC. Endobronchial biopsy in childhood. Chest 2008;133;312-313

Regamey N, Kaiser L. Rhinovirus infections in infants: is RSV ready for the challenge? Eur Respir J 2008 Aug; 32(2):249-51

Schulte D, Cholewa D, Casaulta C, Zachariou Z. German. The role of thoracoscopy in paediatric spontaneous pneumothorax. Praxis 2008: Sep 24;97(19):1033-6.

2007

Latzin P, Frey U, Roiha HL, Baldwin DN, Regamey N, Strippoli MP, Zwahlen M, Kuehni CE. Prospectively assessed incidence, severity, and determinants of respiratory symptoms in the first year of life. Pediatr Pulmonol 2007; 42(1): 41-50.

Latzin P, Sauteur L, Thamrin C, Schibler A, Baldwin D, Hutten GL, Kyburz M, Kraemer R, Riedel T, Frey U. Optimised temperature and deadspace correction improve analysis of multiple breath washout measurements by ultrasonic flowmeter in infants. Pediatr Pulmonol. 2007; 42(10): 888-97

Pachlopnik Schmid JM, Kuehni CE, MD, Roiha HL, Pavlovic R, Strippoli MF, Latzin P, Gallati S, Kraemer R, Dahinden C, Frey U. Maternal tobacco smoking and decreased leukocytes, including dendritic cells in neonates. Ped Res 2007; 61(4): 462-6

Regamey N, Frey U, Deffernez C, Latzin P, Kaiser L. Isolation of human bocavirus from Swiss infants with respiratory infections. Ped Inf Dis J 2007; 26(2): 177-9

Roiha HL, Kuehni CE, Zanolari M, Zwahlen M, Baldwin DN, Casaulta C, Nelle M, Frey U. Alterations of exhaled nitric oxide in preterm infants with chronic lung disease. Eur Resp J Eur Respir J. 2007 ; 29(2): 251-8

Thamrin C, Latzin P, Sauteur L, Riedel T, Hall G, Frey U. Deadspace estimation from CO2 versus molar mass measurements in infants. Pediatr Pulmonol 2007; 42(10): 920-7

Barben J, Casaulta C, Spinas R, Schöni MH. Swiss Working Group for Cystic Fibrosis (SWGCF). Sweat testing practice in Swiss hospitals. Swiss Med Wkly 2007; 137(13-14): 192-8

Bozanich EM, Jánosi TZ, Collins RA, Thamrin C, Turner DJ, Hantos Z, Sly PD. Methacholine responsiveness in mice from 2 to 8 wk of age. J Appl Physiol. 2007; 103(2): 542-6.

Griese M, Latzin P, Kappler M, Weckerle K, Heinzlmaier T, Bernhardt T, Hartl D. alpha1-Antitrypsin inhalation reduces airway inflammation in cystic fibrosis patients. Eur Respir J. 2007; 29(2): 240-50

Hartl D, Latzin P, Hordijk P, Marcos V, Rudolph C, Woischnik M, Krauss-Etschmann S, Koller B, Reinhardt D, Roscher AA, Roos D, Griese M. Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease. Nat Med. 2007 Dec;13(12):1423-30

Hilliard TN, Regamey N, Shute JK, Nicholson AG, Alton EW, Bush A, Davies JC. Airway remodelling in children with cystic fibrosis.Thorax 2007; 62(12): 1074-80

Hutten J, van Eykern LA, Cobben JM, van Aalderen WM. Cross talk of respiratory muscles It is possible to distinguish different muscle activity? Respir Physiol Neurobiol. 2007; 15 158(1):1-2

Latzin P, Beck-Ripp J, Hartl D, Bartenstein A, Noss J, Griese M. 8-Isoprostane in nasally exhaled breath condensate in different pediatric lung diseases.Eur J Med Res 2007;12(1): 21-5

Regamey N, Obregon C, Ferrari-Lacraz S, van Leer C, Chanson M, Nicod LP, Geiser T. Airway epithelial IL-15 transforms monocytes into dendritic cells.Am J Respir Cell Mol Biol. 2007; 37(1): 75-84

Regamey N, Hilliard TN, Saglani S, Zhu J, Scallan M, Balfour-Lynn IM, Rosenthal M, Jeffery PK, Alton EW, Bush A, Davies JC.Quality, size, and composition of pediatric endobronchial biopsies in cystic fibrosis.Chest. 2007; 131(6): 1710-7

de Souza Luna LK, Heiser V, Regamey N, Panning M, Drexler JF, Mulangu S, Poon L, Baumgarte S, Haijema BJ, Kaiser L, Drosten C. Generic detection of coronaviruses and differentiation at the prototype strain level by reverse transcription-PCR and nonfluorescent low-density microarray. J Clin Microbiol. 2007; 45(3): 1049-52

Schneider M, Hirt C, Casaulta C, Barben J, Spinas R, Bühlmann U, Spalinger J, Schwizer B, Chevalier-Porst F, Gallati S. Large deletions in the CFTR gene: clinics and genetics in Swiss patients with CF. Clin Genet. 2007; 72: 30-8

Thamrin C, Gangell CL, Udomittipong K, Kusel MM, Patterson H, Fukushima T, Schultz A, Hall GL, Stick SM, Sly PD. Assessment of bronchodilator responsiveness in preschool children using forced oscillations. Thorax 2007; 62(9): 814-9

2006

Kondo T. Baldwin DR, Nelle M, Frey U. Non-invasive monitoring of chest wall movement in infants using laser. Ped. Pulmonol. 2006

Pfammatter JP, Casaulta C, Pavlovic M, Berdat PA, Frey U, Carrel T. Impor¬tant excess morbidity due to upper airway anomalies in the perioperative course in infant cardiac surgery. Ann Thorac Surg. 2006; 81(3): 1008-12

Henschen M, Stocks J, Brookes I, Frey U. New aspects of airway mechanics in preterm infants. Eur Respir J. 2006 Feb 2; [Epub ahead of print]

Baldwin DN, Pillow JJ, Stocks J, Frey U. Lung-function tests in neonates and infants with chronic lung disease: Tidal breathing and respiratory control. Pediatr Pulmonol. 2006;41(5):391-419

Roiha HL, Kuehni CE, Zanolari M, Zwahlen M, Baldwin DN, Casaulta C, Nelle M, Frey U. Alterations of exhaled nitric oxide in preterm infants with chronic lung disease. Eur Respir J. 2006 Oct 18; [Epub ahead of print]

Latzin P, Kuehni CE, Baldwin DN, Roiha HL, Casaulta C, Frey U. Elevated Exhaled Nitric Oxide in Newborns of Atopic Mothers Precedes Subsequent Respiratory Symptoms. Am J Respir Crit Care Med. 2006 Sep 14

Kraemer R, Delosea N, Ballinari P, Gallati S, Crameri R. Effect of Allergic Broncho-pulmonary Aspergillosis on Lung Function in Children with Cystic Fibrosis. Am J Respir Crit Care Med. 2006 Sep 7; [Epub ahead of print]

Zuercher AW, Horn MP, Que JU, Ruedeberg A, Schoeni MH, Schaad UB, Marcus P, Lang AB. Antibody responses induced by long-term vaccination with an octovalent conjugate Pseudomonas aeruginosa vaccine in children with cystic fibrosis. FEMS Immunol Med Microbiol. 2006 Jul;47(2):302-8

Ritz N, Ammann RA, Casaulta Aebischer C, Schoeni-Affolter F, Schoeni MH. Risk factors for allergic bronchopulmonary aspergillosis and sensitisation to Aspergillus fumigatus in patients with cystic fibrosis. Eur J Pediatr. 2006 Sep;165(9):670

Griese M, Latzin P, Kappler M, Weckerle K, Heinzlmaier T, Bernhardt T, Hartl D. Alpha-1-antitrypsin inhalation reduces airway inflammation in cystic fibrosis patients. Eur Respir J. 2006 Oct 18; [Epub ahead of print]

Schmoldt S, Latzin P, Heesemann J, Griese M, Imhof A, Hogardt M. Clonal analysis of Inquilinus limosus isolates from six cystic fibrosis patients and specific serum antibody response. J Med Microbiol. 2006 Oct;55(Pt 10):1425-33

Hartl D, Latzin P, Zissel G, Krane M, Krauss-Etschmann S, Griese M. Chemokines indicate allergic bronchopulmonary aspergillosis in patients with cystic fibrosis. Am J Respir Crit Care Med. 2006 Jun 15;173(12):1370-6. Epub 2006 Mar 16